Abstract

A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019, and it was known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses (ICTV). we encountered four patients whose only symptom was hiccups, and they were found to be COVID-19 positive with real-time polymerase chain reaction (RT-PCR). Case presentation. Four cases with 45,57,38 and 19 years of age presented with persistent hiccups as the main and only symptom of their disease. All patients were stable and received only symptomatic treatment and were discharged after 14 days that the second swab result came as negative. Discussion and conclusion. In the present study, the researchers have identified 4 cases that had a new, and perhaps rare, symptom-here hiccups-and investigated these cases meticulously and also separately. This report addresses two remarkable factors: firstly, it indicates the importance of the exact examination of those presenting with hiccups, at least by taking a detailed history of patients, a comprehensive physical examination, obtaining basic laboratory work, and also taking a chest X-ray. Secondly, physicians need to prepare for facing the new symptoms of Covid-19 disease. © 2021, Dynasty Publishing House. All rights reserved.