Abstract

Background: Decreased placental volume is associated with higher incidence of small for gestational age (SGA) fetuses and adverse pregnancy outcome (APO). Objective: We used two-dimensional sonography to study the association between placental parameters and UAD sonography with APO in a low-risk obstetric population. Singleton pregnant women at 18 to 24 weeks of gestation enrolled the study. Participants underwent 2D sonography. Fetal biometric and placental parameters were measured. Placental volume was calculated using convex-concave shell formula. Mean pulsatility index (PI) ≥ 1.6 or the mean resistance index (RI) ≥ 0.58 or presence of diastolic notch was considered as abnormal UAD. SPSS version 20 was used for data analysis. Results: In 508 women with singleton pregnancies, APO was found in 30.4. Significant correlations of placental height and volume with neonatal weight were found. Mean placental height and volume was lower in SGA than AGA group (P=0.036 and 0.034, respectively). Mean placental thickness and height was lower in APO group than controls (P=0.030 and P<0.001, respectively). In SGA group, for placental height, the area under the curve (AUC) was 0.678 (P=0.013). With cut-off of 3.4 cm, there was 66.7 sensitivity and 62 specificity. In APO group, for placental height, the AUC was 0.714 (P=0.001).There were no significant differences in mean PI and mean RI between SGA and AGA groups as well as between APO and normal outcome pregnancies. Conclusion: The preferential value of second-trimester placental volume and placental height in predicting SGA compared to Doppler sonography may be concluded. © 2014 AENSI Publisher All rights reserved.