Abstract

Background: Breast cancer is one of the most common cancers in women and has mental and emotional effects, which lead to a decline in their quality of life. This study is aimed at determining the prevalence of severe depression in Iranian women with breast cancer. Methods: This meta-analysis study was conducted at Zabol University of Medical Sciences in 2019. Seven electronic databases were searched and evaluated for original research papers published on the prevalence of severe depression in Iranian women with breast cancer. Finally, 13 articles were selected and analyzed via Comprehensive Meta-Analysis software. Results: Overall, the prevalence of severe depression in Iranian women with breast cancer was 11 (95 CI (7.2, 16.5)). The highest prevalence was 44 in Tehran City in 2015 (95 CI (31, 57.9)), and the lowest prevalence was 0.8 in Qom City in 2017 (95 CI (0.01, 6.2)). A significant statistical correlation was observed between the prevalence of severe depression and sample size (p < 0.05). Conclusion: According to the results of this study, the prevalence of severe depression affects more than one-tenth of women with breast cancer.