Abstract

Objective: The aim of this study was to investigate the geographical distribution of Gastric Cancer (GC) incidence and mortality in the world in 2012, as well as the trend of incidence and mortality of GC during 1975 to 2010 based on the gender. Materials and Methods: In the present study, we extracted the information on the incidence and mortality of GC in 184 countries from the International Agency for Research on Cancer (IARC) (Project GLOBOCAN, 2012). The present study categorized and presented the information on the Age-Standardized Incidence Rate (ASIR) and Age Standardized Mortality Rate (ASMR) of GC based on the continents, world regions based on the development level, WHO regions classification and Human Development Index (HDI). ASIR and ASMR of GC expressed per 100,000 people. Results: The highest ASIR and ASMR of GC occurred in Asia (ASIR=15.8 and ASMR=11.7), less developed regions (ASIR=12.7 and ASMR=10.2), and the WPRO (ASIR=22.8 and ASMR=15.7), and those regions with medium level of HDI (ASIR=14.4 and ASMR=11.8). The incidence and mortality rates of this disease are decreasing in most countries from 1975 to 2010 in the world. Conclusions: The highest incidence and mortality of GC were observed in Asia, less developed regions, and the WPRO and those areas with medium levels of human development index. The incidence and mortality rates of GC were decreasing in both genders and most regions of the world.