Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zabol University of Medical Sciences

Biosynthesis and cytotoxic activity of lead oxide nanoparticles

(2018) Biosynthesis and cytotoxic activity of lead oxide nanoparticles. Green Chemistry Letters and Reviews. pp. 567-572. ISSN 1751-8253

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Abstract

Lead oxide (PbO) is known as an important industrial material. It is a semiconductor that has two crystalline forms, litharge (tetragonal crystalline structure) and massicot (orthorhombic crystalline structure). In this research, lead oxide nanoparticles (PbO-NPs) have been synthesized through the utilization of gelatin as a stabilizer, while its cytotoxic effects were investigated on Neueo2A cancer cell line. The generation of PbO-NPs was confirmed by the UV-Vis spectroscopy, PXRD, TG-DTA, EDX, and FESEM. The results of diffraction patterns of synthesized nanoparticles show the formation of both form alpha-PbO-NPs (tetragonal) and beta-PbO-NPs (orthorhombic). The particles size of synthesized PbO-NPs was calculated to be around 10-20nm. The cytotoxic activity of the synthesized PbO-NPs indicated that concentrations under 30 mu g/mL have insignificant toxicity.

Item Type: Article
Keywords: alpha -PbO-NPs beta-PbO-NPs biosynthesis cytotoxicity green synthesis oxidative stress pbo nanoparticles alpha-pbo exposure antioxidant nanoceria Chemistry Science & Technology - Other Topics
Divisions:
Page Range: pp. 567-572
Journal or Publication Title: Green Chemistry Letters and Reviews
Volume: 11
Number: 4
Identification Number: 10.1080/17518253.2018.1547926
ISSN: 1751-8253
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zbmu.ac.ir/id/eprint/3891

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