(2018) Determination of carbamazepine in urine and water samples using amino-functionalized metal-organic framework as sorbent. Chemistry Central Journal. p. 12. ISSN 1752-153X
Full text not available from this repository.
Abstract
A stable and porous amino-functionalized zirconium-based metal organic framework (Zr-MOF-NH2) containing missing linker defects was prepared and fully characterized by FTIR, scanning electron microscopy, powder X-ray diffraction, and BET surface area measurement. The Zr-MOF-NH2 was then applied as an adsorbent in pipette-tip solid phase extraction (PT-SPE) of carbamazepine. Important parameters affecting extraction efficiency such as pH, sample volume, type and volume of eluent, amount of adsorbent, and number of aspirating/dispensing cycles for sample solution and eluent solvent were investigated and optimized. The best extraction efficiency was obtained when pH of 100 mu L of sample solution was adjusted to 7.5 and 5 mg of the sorbent was used. Eluent solvent was 10 mu L methanol. Linear dynamic range was found to be between 0.1 and 50 mu g L-1 and limit of detection for 10 measurement of blank solution was 0.05 mu g L-1. This extraction method was coupled to HPLC and was successfully employed for the determination of carbamazepine in urine and water samples. The strategy combined the advantages of fast and easy operation of PT-SPE with robustness and large adsorption capacity of Zr-MOF-NH2.
Item Type: | Article |
---|---|
Keywords: | Carbamazepine Pipette-tip solid phase extraction Zirconium-based metal-organic framework Urine analysis solid-phase extraction performance liquid-chromatography molecularly imprinted polymer tandem mass-spectrometry plasma samples waste-water pharmaceutical samples facile synthesis surface-area gas-storage Chemistry |
Divisions: | |
Page Range: | p. 12 |
Journal or Publication Title: | Chemistry Central Journal |
Volume: | 12 |
Identification Number: | 10.1186/s13065-018-0446-x |
ISSN: | 1752-153X |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.zbmu.ac.ir/id/eprint/3858 |
Actions (login required)
View Item |