(2018) The Effect of 8 Weeks Aerobic Training on Serum Levels of Pro-inflammatory Cytokines (IL-17) and Immunoglobulins (IgA, IgM, IgG and IgE) Levels in Patients with Type 2 Diabetes. Annals of Medical and Health Sciences Research. pp. 376-379. ISSN 2141-9248
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Abstract
Sports activities play an important role in immune system function. Multiple short-long-terms, intense, endurance and regular exercise have different effects on immune system. In this study the effect of eight weeks aerobic training on serum levels of pro-inflammatory cytokines (IL-17) and immunoglobulins (IgA, IgM, IgG and IgE) in patients with type 2 diabetes were examined. Methods of study: 60 male type II diabetic patients age ranges from 30 to 50 years old with fasting blood glucose between 150-250 mg/dl were selected by cross-sectional clinical trial study. An eight-week program of aerobic exercise three hours per week, each week one hour training session was performed for them. Then 5 ml blood sample before starting the first session and 24 hours after eight weeks of training was taken. Serum levels of immunoglobulins E, G, M, A and IL-17 in patients before and after exercise were measured by ELISA method and the results were analyzed using statistical tests. Results: The results showed that serum immunoglobulin levels of patients after 8 weeks of aerobic exercise significantly altered but the serum levels of IL-17 was not significantly changed. Conclusion: Significant changes in the levels of serum immunoglobulin levels of athlete's diabetic patients hoping that exercise can improve their immune systems function. No significant changes in IL-17 after 8 weeks of training were due to the low-intensity exercise that requires further investigation.
Item Type: | Article |
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Keywords: | 8 weeks aerobic training Serum levels of pro-inflammatory cytokines (IL-17) Immunoglobulins (IgA, IgM, IgG, IgE) levels Type 2 diabetes exercise life Health Care Sciences & Services |
Divisions: | |
Page Range: | pp. 376-379 |
Journal or Publication Title: | Annals of Medical and Health Sciences Research |
Volume: | 8 |
Number: | 6 |
ISSN: | 2141-9248 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.zbmu.ac.ir/id/eprint/3784 |
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