(2019) Novel Therapies for Biofilm-Based Candida spp. Infections. In: Advances in Microbiology, Infectious Diseases and Public Health, Vol 13. Advances in Experimental Medicine and Biology, 1214 . Springer International Publishing Ag, Cham, pp. 93-123. ISBN 978-3-030-35469-5; 978-3-030-35468-8
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Abstract
The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed patients, and in individuals with continued antimicrobial treatments. Candida spp. are the most common yeasts involved in these disorders, being associated with a high rate of antifungal resistance and an increased ability to form biofilms, which make the treatment of these infections difficult. This review aims to present and discuss the main biofilm-related infections cause by several Candida spp. and novel therapies that are currently available in the clinical, scientific and academic environment. New drugs with promising antifungal activity, natural approaches (e.g. probiotics, essential oils, plant extracts, honey) and a final consideration on alternative methodologies, such as photodynamic therapy are presented and discussed.
| Item Type: | Book Section |
|---|---|
| Keywords: | Biofilms Candida spp. Drugs Essential oil Honey Infection Photodynamic therapy Plant extract Prebiotic Probiotic Resistance photodynamic antimicrobial chemotherapy quorum-sensing molecule blood-stream infection in-vitro amphotericin-b biological evaluation antifungal activity essential oils oral candida fluconazole-resistant |
| Divisions: | |
| Title of Book: | Advances in Microbiology, Infectious Diseases and Public Health, Vol 13 |
| Page Range: | pp. 93-123 |
| Volume: | 1214 |
| Publisher: | Springer International Publishing Ag |
| Identification Number: | 10.1007/5584₂₀₁₉₄₀₀ |
| ISBN: | 978-3-030-35469-5; 978-3-030-35468-8 |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.zbmu.ac.ir/id/eprint/3734 |
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