Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zabol University of Medical Sciences

Areca catechu-From farm to food and biomedical applications

(2020) Areca catechu-From farm to food and biomedical applications. Phytotherapy Research. pp. 2140-2158. ISSN 0951-418X

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Abstract

The family Arecaceae includes 181 genera and 2,600 species with a high diversity in physical characteristics.Arecaplants, commonly palms, which are able to grow in nearly every type of habitat, prefer tropical and subtropical climates. The most studied speciesAreca catechuL. contains phytochemicals as phenolics and alkaloids with biological properties. The phenolics are mainly distributed in roots followed by fresh unripe fruits, leaves, spikes, and veins, while the contents of alkaloids are in the order of roots, fresh unripe fruits, spikes, leaves, and veins. This species has been reputed to provide health effects on the cardiovascular, respiratory, nervous, metabolic, gastrointestinal, and reproductive systems. However, in many developing countries, quid from this species has been associated with side effects, which include the destruction of the teeth, impairment of oral hygiene, bronchial asthma, or oral cancer. Despite these side effects, which are also mentioned in this work, the present review collects the main results of biological properties of the phytochemicals inA. catechu. This study emphasizes the in vitro and in vivo antioxidant, antimicrobial, anticancer, and clinical effectiveness in humans. In this sense,A. catechuhave demonstrated effectiveness in several reports through in vitro and in vivo experiments on disorders such as antimicrobial, antioxidant, or anticancer. Moreover, our findings demonstrate that this species presents clinical effectiveness on neurological disorders. Hence,A. catechuextracts could be used as a bioactive ingredient for functional food, nutraceuticals, or cosmeceuticals. However, further studies, especially extensive and comprehensive clinical trials, are recommended for the use ofArecain the treatment of diseases.

Item Type: Article
Keywords: alkaloids Areca betel nut human health phenolics adverse birth outcomes chewing betel-nut hepatocellular-carcinoma antioxidant activities quid use antibacterial extract risk l. schizophrenia Pharmacology & Pharmacy
Divisions:
Page Range: pp. 2140-2158
Journal or Publication Title: Phytotherapy Research
Volume: 34
Number: 9
Identification Number: 10.1002/ptr.6665
ISSN: 0951-418X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zbmu.ac.ir/id/eprint/3488

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