Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zabol University of Medical Sciences

Chemical composition, antioxidant activity and in vitro antibacterial activity of Achillea wilhelmsii C. Koch essential oil on methicillin-susceptible and methicillin-resistant Staphylococcus aureus spp

(2015) Chemical composition, antioxidant activity and in vitro antibacterial activity of Achillea wilhelmsii C. Koch essential oil on methicillin-susceptible and methicillin-resistant Staphylococcus aureus spp. 3 Biotech. pp. 39-44. ISSN 2190572X (ISSN)

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Abstract

The present study investigated the chemical composition of the essential oil (EO) from aerial parts (flowering stage) of Achillea wilhelmsii C. Koch by GC–MS. In addition, the antioxidant activity of the EO as well as its antimicrobial activity against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MRSA) strains was tested. Antioxidant activity was measured by the ability of the EO to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals while the antimicrobial activity was assessed by the disc-diffusion method. In total, 52 compounds were recognized, accounting for 97.33 of the EO. The main compounds in the EO were carvacrol (22.49 ), dihydrocarvone (13.23 ), linalool (12 ), 1,8-cineol (11.42 ), camphene (8.31 ), thymol (5.28 ), camphor (3.71 ), pulegone (2.82 ) α-terpineol (2.11 ), bornyl acetate (1.14 ), and farganol (1.01 ). The EC50value of the EO was 0.01 and 0.08 mg/mL for the antioxidant and DPPH-scavenging ability, respectively. A. wilhelmsii EO affected methicillin-sensitive Staphylococcus aureus (MSSA) and MRSA, but the impact was more effective on MSSA. © 2014, The Author(s).

Item Type: Article
Keywords: Achillea wilhelmsii Antioxidant activity Essential oil (EO) GC–MS MRSA MSSA Staphylococcus aureus 1,1 diphenyl 2 picrylhydrazyl Achillea wilhelmsii essential oil alpha phellandrene alpha thujene alpha tocopherol ascorbic acid borneol bornyl acetate butylated hydroxyanisole camphene camphor carvacrol caryophyllene oxide cineole dihydrocarvone elemol essential oil farganol linalool nonanol para cymene pinene pulegone sabinene terpinene terpineol thymol unclassified drug verbenone antibacterial activity antibiotic sensitivity Article chemical composition colony forming unit controlled study disk diffusion DPPH radical scavenging assay growth inhibition in vitro study mass fragmentography methicillin resistant Staphylococcus aureus methicillin susceptible Staphylococcus aureus minimum inhibitory concentration nonhuman priority journal Dryobalanops
Divisions:
Page Range: pp. 39-44
Journal or Publication Title: 3 Biotech
Volume: 5
Number: 1
Identification Number: 10.1007/s13205-014-0197-x
ISSN: 2190572X (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zbmu.ac.ir/id/eprint/3238

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