Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zabol University of Medical Sciences

Clinical and epidemiological aspects of multiple sclerosis in children

(2017) Clinical and epidemiological aspects of multiple sclerosis in children. Iranian Journal of Child Neurology. pp. 37-43. ISSN 17354668 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Objective Overall, 2-5 of patients with multiple sclerosis (MS) experienced the first episode of disease before the age 18 years old. Since the age of onset among children is not similar to that in general population, clinicians often fail to early diagnose the disease. This study aimed to determine the epidemiological and clinical patterns of MS among Iranian children. Materials & Methods In this cross-sectional study carried out in Iran in 2014-2015, information was collected using a checklist with approved reliability and validity. Method sampling was consensus. Data were analyzed using frequency, mean and standard deviation indices by means of SPSS ver. 20 software. Results Totally, 177 MS children were investigated. 75.7 of them were female. Mean (SD), minimum and maximum age of subjects were 15.9 (2), 7 and 18 yr, respectively. The most reported symptoms were sensory (28.2), motor (29.4), diplopia (20.3) and visual (32.8). Primary MRI results showed 91.5 and 53.1 periventricular and spinal cord lesions, respectively. Conclusion MS is significantly more common among women. The most common age of onset is during the second decades. Sensory and motor problems are the most symptoms, while, periventricular and spinal cord lesions are the most MRI results. © 2017, Iranian Child Neurology Society. All rights reserved.

Item Type: Article
Keywords: Children Clinical Epidemiology Iran Multiple sclerosis adolescent adult Article ataxia behavior disorder brain damage checklist child consensus content validity cranial nerve paralysis cross-sectional study defecation disorder diplopia dysarthria eye movement disorder family history female human Iranian people major clinical study male motor dysfunction neuroimaging nuclear magnetic resonance imaging reliability scotoma seizure sensory dysfunction spinal cord lesion urinary tract disease visual disorder visual impairment
Divisions:
Page Range: pp. 37-43
Journal or Publication Title: Iranian Journal of Child Neurology
Volume: 11
Number: 2
ISSN: 17354668 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zbmu.ac.ir/id/eprint/3062

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