(2015) Chemical composition, antioxidant activity and in vitro antibacterial activity of Achillea wilhelmsii C. Koch essential oil on methicillin-susceptible and methicillin-resistant Staphylococcus aureus spp. 3 Biotech. pp. 39-44. ISSN 2190-572X (Print) 2190-5738 (Linking)
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Abstract
The present study investigated the chemical composition of the essential oil (EO) from aerial parts (flowering stage) of Achillea wilhelmsii C. Koch by GC-MS. In addition, the antioxidant activity of the EO as well as its antimicrobial activity against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MRSA) strains was tested. Antioxidant activity was measured by the ability of the EO to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals while the antimicrobial activity was assessed by the disc-diffusion method. In total, 52 compounds were recognized, accounting for 97.33 of the EO. The main compounds in the EO were carvacrol (22.49 ), dihydrocarvone (13.23 ), linalool (12 ), 1,8-cineol (11.42 ), camphene (8.31 ), thymol (5.28 ), camphor (3.71 ), pulegone (2.82 ) alpha-terpineol (2.11 ), bornyl acetate (1.14 ), and farganol (1.01 ). The EC50 value of the EO was 0.01 and 0.08 mg/mL for the antioxidant and DPPH-scavenging ability, respectively. A. wilhelmsii EO affected methicillin-sensitive Staphylococcus aureus (MSSA) and MRSA, but the impact was more effective on MSSA.
| Item Type: | Article |
|---|---|
| Keywords: | Achillea wilhelmsii Antioxidant activity Essential oil (EO) Gc-ms Mrsa Mssa Staphylococcus aureus |
| Divisions: | |
| Page Range: | pp. 39-44 |
| Journal or Publication Title: | 3 Biotech |
| Volume: | 5 |
| Number: | 1 |
| Identification Number: | 10.1007/s13205-014-0197-x |
| ISSN: | 2190-572X (Print) 2190-5738 (Linking) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.zbmu.ac.ir/id/eprint/2940 |
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