Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zabol University of Medical Sciences

New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles

(2017) New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles. Cancer Gene Therapy. pp. 233-243. ISSN 0929-1903

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Official URL: <Go to ISI>://WOS:000403524800001

Abstract

Cancer is one of the leading cause of death in the world with the prevalence of >10 million mortalities annually. Current cancer treatments include surgical intervention, radiation, and taking chemotherapeutic drugs, which often kill the healthy cells and result in toxicity in patients. Therefore, researchers are looking for ways to be able to eliminate just cancerous cells. Intra-tumor heterogeneity of cancerous cells is the main obstacle on the way Of an effective cancer treatment. However, better comprehension Of molecular basis of tumor and the advent of new diagnostic technologies can help to improve the treatment of various cancers. Therefore, study of epigenetic changes, gene expression of cancerous cells and employing methods that enable us to correct or minimize these changes is critically important. In this paper, we will review the recent advanced strategies being used in the field of cancer research.

Item Type: Article
Keywords: targeted drug-delivery near-infrared light in-vivo tumor vasculature noncoding rnas breast-cancer photoswitchable nanoparticles liposomal doxorubicin gold nanoparticles systemic delivery
Divisions:
Page Range: pp. 233-243
Journal or Publication Title: Cancer Gene Therapy
Volume: 24
Number: 6
Identification Number: 10.1038/cgt.2017.16
ISSN: 0929-1903
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zbmu.ac.ir/id/eprint/2391

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