(2017) Cytotoxic activity of biosynthesized Ag Nanoparticles by Plantago major towards a human breast cancer cell line. Rendiconti Lincei-Scienze Fisiche E Naturali. pp. 693-699. ISSN 2037-4631
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Abstract
Silver nanoparticles were synthesized by bio-inspired route, a cost effective and fast synthesis method. Structural and morphological characterization of nanoparticles was performed by UV-visible absorption spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction and transmission electron microscopy. The cytotoxic activity of both nanoparticles and Plantago major extract containing nanoparticles against a human breast cancer cell (MCF-7) was studied in vitro. MTT (3-4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays were performed using various concentrations of P. major extract (alone) and extract containing AgNPs ranging from 0.5 to 2.5 A mu g/ml. Data analysis showed significant level of cytotoxic activity. The potential cytotoxicity of silver nanoparticles in the treatment of breast cancer is discussed.
Item Type: | Article |
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Keywords: | cytotoxic breast cancer plantago major mtt biosynthesis agnps carbon-paste electrode silver nanoparticles green synthesis oxide nanoparticles stachys-lavandulifolia antibacterial activity biological-activities anticancer activity gold nanoparticles mcf-7 |
Divisions: | |
Page Range: | pp. 693-699 |
Journal or Publication Title: | Rendiconti Lincei-Scienze Fisiche E Naturali |
Volume: | 28 |
Number: | 4 |
Identification Number: | 10.1007/s12210-017-0641-z |
ISSN: | 2037-4631 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.zbmu.ac.ir/id/eprint/2288 |
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