(2018) Recent advances on nanomaterial based electrochemical and optical aptasensors for detection of cancer biomarkers. Trac-Trends in Analytical Chemistry. pp. 103-115. ISSN 0165-9936
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Abstract
Cancer is a real Menace to all societies globally since it is the leading cause of premature mortality in men and women. The incidence of malignancies is enhancing as a result of plenty factors. Physically and economically concerns that occur in cancers patients cannot be neglected. However, current diagnostic methods and cure duration do not fulfill patients requirements. Therefore, it is essential to detect and diagnose cancer biomarkers as soon as possible and overcome the current burdens. Novel aptasensors is emerging as one of the most promising strategies for early recognition of cancer. Aptamers an artificial DNA or RNA sequences, possess plenty of merits such as easy production, modification of their structure, lower immunogenicity, and high affinity to target that pave the way for early detection of cancer biomarkers. This review attempts to ist novel and advanced investigation progress of aptamers in biosensor platforms for diagnosing of malignancies. (C) 2017 Elsevier B.V. All rights reserved.
Item Type: | Article |
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Keywords: | cancer aptamer biosensor biomarker detection surface-plasmon resonance rolling-circle-amplification hybridization chain-reaction nitrogen-doped graphene label-free ultrasensitive detection sensitive detection modified electrode adenosine-triphosphate amplified detection |
Divisions: | |
Page Range: | pp. 103-115 |
Journal or Publication Title: | Trac-Trends in Analytical Chemistry |
Volume: | 100 |
Identification Number: | 10.1016/j.trac.2017.12.019 |
ISSN: | 0165-9936 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.zbmu.ac.ir/id/eprint/2259 |
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